Recherche sur les réseaux cérébraux cortico-subcorticaux impliqués dans les crises d'épilepsie focale et les comorbidités psychiatriques qui peuvent y être associées.

Research on the cortico-subcortical brain networks involved in focal epileptic seizures and psychiatric comorbidities that may be associated with them.

• Auteur / Autrice : Léa Chibany
• Direction : Jérôme Aupy
• Type : Projet de thèse
• Discipline(s) : Neurosciences
• Date : Inscription en doctorat le 02/01/2024
• Etablissement(s) : Bordeaux
• Ecole(s) doctorale(s) : École doctorale Sciences de la vie et de la santé (Talence, Gironde ; 1993-....)
• Partenaire(s) de recherche : Laboratoire : Bézard

Mots clés

Mots clés libres

Epilepsie

Comorbidités

Seeg

Réseaux x

Epilepsy

Comorbidities

Networks

Epilepsy

Anxiety

Résumé

The basal ganglia, along with the thalamus and cortex, form a vast network involved in behavioral control and procedural learning. Various dysfunctions within this cortico- subcortical network may be implicated in movement disorders such as idiopathic Parkinson's disease (PD), dopa-induced dyskinesias, or hyperkinetic epilepsy seizures. The expression of hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity within this cortico- subcortical network, spanning a wide range of frequencies (1,2). In this project, we propose to study cortico-subcortical oscillations and their synchronization during hyper